|
|
||||||||
Laboratory of Biochemistry, Department of Dairy Science, University of Illinois, Urbana
ABSTRACT
The new-born of many species, including the bovine, acquire passive immunity by ingestion of the immune globulins present in the maternal colostrum. These immune globulins appear in the blood stream of the new-born and are apparently unchanged by the transfer, in that they possess the properties of the immune globulins in the colostrum (7, 8, 16–19).
The source of the immune globulins present in the colostrum has not been demonstrated as adequately. Early investigators (2, 10) could find no differences between the immune globulins isolated from the blood and from the colostrum of the bovine dam, and concluded that they were probably transferred directly from the blood into the mammary gland. Smith (16, 17, 18) and Smith and Holm (19) compared the amino acid composition and the electrophoretic properties of the immune globulin fractions isolated from bovine colostrum and milk with
1- (or T-) and the
2- (or
-) globulins isolated from the maternal blood serum and concluded that they were closely related but not identical.
1 Supported in part by aid from the Rockefeller Foundation.
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |