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A Study of the Secretion of Iodine in Milk of Dairy Cows, Using Daily Oral Doses of I^{1311, 2,}

University of Tennessee — Atomic Energy Commission, Agricultural Research Program Oak Ridge, Tennessee, and Dairy Department, University of Tennessee, Knoxville

ABSTRACT

The authors have traced the secretion of iodine to the fat and nonfat fractions of milk, through the normal pathways of excretion and to its retention in the blood and thyroid. They have also demonstrated the usefulness of the isotope dilution method for studying trace mineral metabolism. Editor.

The metabolism of iodine by the dairy cow has been of interest for many years. However, owing to the lack of reliable techniques adaptable to routine analyses, the secretion of iodine into milk has not been studied in detail. The advent of nuclear fission markedly increased the amount of research concerning iodine metabolism by providing radioactive nuclides which, though chemically indistinguishable from the nonradioactive iodine, are readily detected by their reactions. Also, the observation of Van Middlesworth (16) that radioactive iodine with a half-life of 8 days could be detected in the thyroids of cattle in many parts of the country in the summer of 1954, made it of more than academic interest to learn more about the secretion of iodine into milk.

¹ This manuscript is published with the permission of the Director of the University of Tennessee Agricultural Experiment Station, Knoxville.

² This work was completed under Contract No. AT-40-1-GEN-242 between the University of Tennessee, College of Agriculture, and the Atomic Energy Commission. The radioactive materials used in this work were obtained from the Oak Ridge National Laboratory on allocation from the United States Atomic Energy Commission.

³ Present address: Division of Chemistry, University of Tennessee, Memphis.

This article has been cited by other articles:

				B. Kahn, C. P. Straub, and I. R. Jones Radioiodine in Milk of Cows Consuming Stored Feed and of Cows on Pasture Science, December 21, 1962; 138(3547): 1334 - 1335. [Abstract] [PDF]