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The Effect of Different Levels of Iodide Feeding on Serum Inorganic and Protein-Bound Iodine, with a Note on the Frequency of Administration Required to Maintain a High Level of Serum Inorganic Iodine¹

Department of Dairy Science, Ohio Agricultural Experiment Station, Wooster

ABSTRACT

This study was designed to determine the effects of normal dietary intake of supplemental iodine (KI) on the serum inorganic iodine and the protein-bound iodine levels of cattle. The application of the results to the frequency of iodine treatment in actinomycosis and other mycotic infections is made. Two mature cows were selected for the experiment. Editor.

Previous experiments (3) showed that the feeding of thyroprotein at the rate of 15 or 25 g. per day resulted in high levels of serum inorganic iodine. The protein-bound iodine (PBI) levels in the serum also were much higher than would be expected in the absence of any clinical evidence of hyperthyroid activity. These high PBT levels were assumed to be partly due to the formation of noncalorigenic PBI resulting from the combination of inorganic iodine in thyroprotein with certain serum protein constituents (3) and also to the presence of noncalorigenic iodinated compounds other than thyroxine in the thyroprotein, which have been demonstrated by Friedberg and Reineke (2).

¹ Journal Article No. 77-55. Ohio Agricultural Experiment Station.