HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Richards, C. R. Articles by Weaver, H. G. Search for Related Content PubMed Articles by Richards, C. R. Articles by Weaver, H. G.

The Effect of Synthalin a on Blood Sugar in Dairy Cattle¹

Department of Animal and Poultry Industry, University of Delaware, Newark

ABSTRACT

The effect of synthalin A (decamethylenediguanidine) upon blood glucose level in the bovine has been reported from studies with six dairy calves and a mature cow. In calves, dosages of 1.0 mg. per pound body weight given intramuscularly had little effect. A dosage of 1.3 mg. per pound resulted in an initial hyperglycemia followed by a marked hypoglycemia, but levels as low as those reported in cows with ketosis were not approached. At 1.5 mg. per pound dosages, or above, blood levels of glucose were lowered to less than 40 mg. % (some were near 10 mg. %). A dosage of 1.0 mg. per pound in the mature cow had an apparent hyperglycemic effect, but no hypoglycemia resulted. When 1.4 mg. per pound was injected, a pronounced initial hyperglycemia was followed by a marked hypoglycemia.

The blood glucose levels of the mature and immature bovine are drastically affected by synthalin A.

¹ Delaware Agricultural Experiment Station Miscellaneous Paper No. 229.