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The Effect of Phenothiazine upon Thyroid Function in Dairy Animals as shown by Radioiodine^{1, 2,}

Department of Dairy Husbandry, University of Missouri, Columbia

ABSTRACT

Commercial phenothiazine, when administered at the rate of 2 g. per day to dairy heifers, reduced the uptake of I¹³¹ but did not induce hypothyroidism, as shown by the release rates of thyroid hormone from the gland. Thus at the dosage administered phenothiazine does not act as a goitrogenic agent.

¹ Contribution from the Mo. Agricultural Experiment Station. Journal Series No. 1622. Approved by the Director.

² Aided-in-part by a grant from the U. S. Atomic Energy Commission [Contract No. AT (11-1)-301].