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Journal of Dairy Science Vol. 36 No. 7 772-777
© 1953 by American Dairy Science Association ®
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The Effect of Relaxin and Mechanical Dilation on the Bovine Cervix1

Edmund F. Graham2 and Arthur E. Dracy

South Dakota Agricultural Experiment Station, Brookings

ABSTRACT

These experiments were conducted to determine the possibility of dilating-the cervix to facilitate the ease of collecting ova.

The administration of relaxin in conjunction with an estrogen served to relax the cervical muscles. Estrogen alone as judged by the pilot cow gave no cervical relaxation. The minimum dosage of relaxin which gave cervical relaxation was 250 G.P.U.; the optimum, about 1,500 G.P.U. A suitable mechanical instrument was designed for dilating the cervix. However, the instrument must be used with the aid of relaxin when used 5 days post estrus. Histological studies of biopsies from the cervix and uterus indicated no signs of trauma from either the relaxin or the instrument.


FOOTNOTES

1 Approved for publication by the Director of the South Dakota Agricultural Experiment Station as Journal Series No. 282.

2 These data are taken from a thesis presented to the graduate school of South Dakota State College by the senior author in partial fulfillment of the requirement for the Master of Science degree.




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Relaxin's Physiological Roles and Other Diverse Actions
Endocr. Rev., April 1, 2004; 25(2): 205 - 234.
[Abstract] [Full Text] [PDF]




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