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The Response of Hormonally Induced Bovine Mammary Tissue to Anterior Pituitary Hormones

Bureau of Dairy Industry, U. S. Department of Agriculture, Washington, D. C.

ABSTRACT

The lactation response of dairy heifers to the injection of anterior pituitary hormones has been investigated. Milk production was found to be much greater in heifers in which the udder was developed with stilbestrol than in heifers in which a combination of stilbestrol and progesterone was used. Prolactin had only a slight stimulatory effect, if any, upon the induced lactations. Thyrotropic hormone was found to stimulate lactation markedly. The most stimulation, however, was obtained by the administration of a growth hormone preparation. These effects were partly a result of thyrotropic hormone contamination of this preparation, but our experiments indicate that growth hormone per se has galactopoietic effects.