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Journal of Dairy Science Vol. 35 No. 9 733-737
© 1952 by American Dairy Science Association ®
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The Effect of Various Dosage Levels of Crystalline Lindane on the Concentration of Lindane in Cow's Milk1

Ray E. Ely and L. A. Moore

Bureau of Dairy Industry

H. D. Mann and R. H. Carter

Bureau of Entomology and Plant Quarantine, Agricultural Research Administration, U. S. D. A.

ABSTRACT

Nine milking dairy animals were fed various dosage levels of crystalline lindane as a 10 per cent solution in soybean oil. The dosage levels ranged from 25 to 2,000 mg. daily, which is equivalent to from 0.07 to 6.22 mg. per kilogram of body weight daily.

When daily dosages of less than 0.36 mg. per kilogram of body weight were given to milking cows, very little could be detected in the milk by chemical methods. When increasing dosage levels above 0.36 mg. per kilogram of body weight were given, progressive increases in the concentration of lindane in the milk were secured.

Comparison of the concentrations of lindane in the milk with the concentrations of DDT in the milk of other cows indicates that approximately the same amounts are excreted in the milk when comparable intakes are given.

The concentration of lindane in the milk dropped rapidly when the dosage was discontinued, but detectable amounts were still excreted for approximately 30 days in the milk of one animal that previously had received 2 g. of lindane daily. None of the animals showed symptoms of any physiological effect from any of the dosage levels fed.

FOOTNOTES

1 This work was done with funds made available by the Agricultural Research and Marketing Act of 1946.






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Copyright © 1952 by the American Dairy Science Association ®.