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The Effect of Vaccination with Brucella Abortus Vaccine (Strain 19) on Certain Blood Constituents in Young Heifers¹

Department of Dairy Husbandry and Biochemistry College of Agriculture, University of Madison, Wisconsin

ABSTRACT

These studies show that blood plasma vitamin C and A levels are reduced by vaccination with B. abortus vaccine (strain 19). The vitamin C levels do not return completely to normal after 1 wk. as do the vitamin A levels. Vitamin C or A in addition to the normal diet had no effect on the course of blood plasma levels, except to maintain them above that for calves not receiving the supplement.

A rise in rectal temperatures followed closely the drop in blood plasma vitamin C and may suggest a relationship between the increase in body temperature and a lowering of blood plasma ascorbic acid.

Leucocyte count increased the day following inoculation. Differential count showed that the neutrophiles increased, the lymphocytes decreased, and the mono-cytes and eosinophiles slightly increased and decreased, respectively, by this type of vaccination.

¹ Published with the approval of the director of the Wisconsin Agricultural Experiment Station.

² Present address: Department of Dairy Husbandry, Purdue University, Lafayette, Ind.