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Choline Studies with Young Dairy Calves. II. Effect of Milk and Other Supplements on Blood Choline Levels¹

Departments of Agricultural Chemistry and Dairy Husbandry, Purdue University, Agricultural Experiment Station, Lafayette, Indiana

ABSTRACT

1. Removal of milk from the diets of calves at 5 weeks of age resulted in a drop in blood choline values.
   
2. Feeding choline chloride or choline chloride and methionine did not increase blood choline levels.
   
3. While not conclusive, some data are presented that indicate returning milk to the diet of calves caused elevation of blood choline.
   
4. Evidence is presented which indicates that a component of milk other than choline or methionine may influence blood choline levels.
   
5. Intravenous injections of choline chloride produced only a temporary rise of the choline content of the blood. It was rapidly removed from the blood stream. Injections of 2 g. proved to be fatal.
   

¹ Journal Paper no. 301 of the Purdue University Agricultural Experiment Station.

² Now at North Carolina State College of Agriculture, Raleigh.