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Journal of Dairy Science Vol. 30 No. 6 361-369
© 1947 by American Dairy Science Association ®
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The Effect of Sulfanilamide in the Diluent upon Fertility of Bull Semen

G. W. Salisbury and G. B. Knodt1

Laboratory of Animal Breeding and Artificial Insemination, Department of Animal Husbandry, Cornell University, Ithaca, N. Y.

ABSTRACT

Three separate experiments involving a total of 8,498 inseminations were conducted to determine the effect on fertility of bull semen of adding sulfanilamide to the yolk-citrate diluent at the rate of 300 mg. per 100 ml. In the first experiment no benefit was observed. In the next two investigations, where the citrate buffer containing sulfanilamide was protected from direct light rays, an increase in fertility by use of the sulfanilamide was obtained. This improvement amounted to 6.1 per cent of the cows inseminated in the second experiment and 4.5 per cent in the third.

The sulfanilamide appeared to influence all semen samples in the same direction, for, in the third experiment, no significant interactions were observed between the treatments and either bulls or first and second ejaculates. These results are interpreted as indicating that the beneficial effects of sulfanilamide on fertility largely are metabolic ones, rather than due to bacterial control alone.


FOOTNOTES

1 Now at Pennsylvania State College, State College, Pennsylvania.




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G. W. SALISBURY and N. L. VANDEMARK
Sulfa Compounds in Reversible Inhibition of Sperm Metabolism by Carbon Dioxide
Science, November 29, 1957; 126(3283): 1118 - 1119.
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