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Copper and Iron in the Blood Serum of Dairy Cows^1,2,3,

U. S. Plant, Soil, and Nutrition Laboratory, Ithaca, New York

Walter J. Peterson, Hartlee M. Baxley and Claude D. Grinnells

Department of Animal Industry, North Carolina State College, Raleigh

ABSTRACT

1. The means for serum iron, serum copper, hemoglobin, and cell volume in sixteen dairy animals were 100 µg. per 100 ml., 162 µg. per 100 ml., 9.9 gm. per 100 ml., and 32 per cent of total volume, respectively. The errors of estimate are given.
   
2. No evidence was obtained that serum iron changed with age. Serum copper and hemoglobin changed significantly with advancing age. The copper values ranged from about 90 µg. per 100 ml. in calves to 114 µg. in 4- to 7-year-old cows, and the hemoglobin increased from 9.08 to 10.64 gm. Per 100 ml. of blood in these age classes.
   
3. There was no significant difference among breeds with respect to any of the measurements.
   
4. For serum iron, serum copper, and hemoglobin, there were pronounced variations from period to period. These variations were irregular with ranges as follows: serum iron, 130.3 to 183.9 µg. per 100 ml.; serum copper, 87.3 to 116.3 µg. per 100 ml.; and hemoglobin, 9.44 to 10.07 gm. per 100 ml.
   
5. No evidence was obtained that serum iron and serum copper are correlated in any way. Hemoglobin and cell volume, in general, were correlated positively.
   

¹ Read before the Division of Biological Chemistry, American Chemical Society meeting, Chicago, Illinois, September 9, 1946.

² Approved for publication as Paper No. 248 of the Journal Series of the North Carolina Agricultural Experiment Station.

³ The authors wish to acknowledge the assistance of Dr. H. L. Lucas of the Institute of Statistics, North Carolina State College, Raleigh.