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The Effect of Sulfanilamide upon the Livability and Metabolism of Bovine Spermatozoa

Department of Animal Husbandry, Cornell University, Ithaca, New York

ABSTRACT

1. The addition of 300 mg. of sulfanilamide per 100 ml. of yolk-citrate diluent, gave a significant improvement in the livability of ejculated bull spermatozoa over a 20-days-storage period and prevented bacterial growth.
   
2. Sulfanilamide depressed glucose and oxygen utilization at all concentrations studied.
   
3. The accumulation of lactic acid was increased both absolutely and in relation to the glucose utilized in the presence of sulfanilamide.
   

^* The authors are indebted to Merck and Co., Inc., Rahway, N. J., for the supplies of sulfanilamide and to Professor I. C. Gunsalus, Laboratory of Bacteriology, Cornell University, for many helpful suggestions.

This article has been cited by other articles:

				G. W. SALISBURY and N. L. VANDEMARK Sulfa Compounds in Reversible Inhibition of Sperm Metabolism by Carbon Dioxide Science, November 29, 1957; 126(3283): 1118 - 1119. [PDF]