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Ascorbic Acid Stimulation in the Blood Plasma of Dairy Cattle Produced by the Ingestion of Chlorobutanol^*

Dairy Husbandry Section and the Chemical Section of the Michigan Agricultural Experiment Station, East Lansing

ABSTRACT

1. Four calves, 7 heifers, 11 cows and 7 bulls were fed various amounts of chlorobutanol for as long as 105 days as a supplement to a standard alfalfa hay ration.
   
2. The ingestion of chlorobutanol served to elevate ascorbic acid in the blood plasma of all of the animals.
   
3. Doses of 10 grams or more of chlorobutanol produced mild anesthetic effects in the animals but the maximum concentration of ascorbic acid in the blood plasma was obtained within a few days.
   
4. No deleterious effects were observed when 5-gram doses were administered for long periods of time.
   
5. A sex difference was noted in the amount of chlorobutanol required to produce a significant increase in plasma ascorbic acid.
   

^* Published with the approval of the Director of the Agricultural Experiment Station as Journal Article no. 617 (n.s.).