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Departments of Biochemistry and Dairy Husbandry, University of Wisconsin, Madison
ABSTRACT
The results of these experiments have shown: (a) that the ascorbic acid content of plasma averaged 0.39 mg. per cent for cows of all breeds studied; (b) that there is a difference between breeds with the Holstein lower than the Guernsey; (c) that there is a higher concentration of ascorbic acid in the plasma of the cow in mid to late estrum than there is in diestrum; (d) that generally speaking there is no difference between good and poor breeders in their peak concentrations of ascorbic acid during estrum; (e) that the subcutaneous ascorbic acid therapy of "hard to settle" cows results in a positive response in 60 per cent of the cases treated; (f) that ascorbic acid therapy does not correct cases of cystic ovary or other anatomical abnormalities; and, (g) that
-tocopherol proved ineffective in restoring tone to a toneless uterus.
From these researches the conclusion is evident that ascorbic acid is intimately associated with the early phases of the reproductive processes and it can be successfully used as a therapeutic measure in treating certain types of sterility in the cow.
1 Published with the approval of the Director of the Wisconsin Agricultural Experiment Station.
These studies were supported in part by funds from the Wisconsin Alumni Research Foundation.
The authors are indebted for the cooperation and help given them by Dr. A. McDermid of the Rock County Breeders Association.
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