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The Relation of Vitamin D to Calcium and Phosphorus Retention in Cattle as Shown by Balance Trials

Divisions of Dairy Husbandry and Agricultural Biochemistry, University of Minnesota, St. Paul, Minnesota

ABSTRACT

The fact that a calf has a definite vitamin D requirement and suffers from a deficiency of this factor in its ration has been demonstrated by the published work of Rupel, Bohstedt and Hart (1), Beehdel, Landsburg and Hill (2), Huffman (3), and by unpublished work of Ghillickson (4) in which experimental "rickets" developed when vitamin D was withheld and disappeared when this factor was added to the ration. Rupel, Bohstedt and Hart (1), and Bechdel, Landsburg and Hill (2) have reported an increased ash percentage in certain representative bones, and an improvement in the concentration of calcium and inorganic phosphorus in the blood plasma following vitamin D therapy of animals suffering from experimental "rickets," which gives indirect evidence of a beneficial effect of vitamin D on the calcium and phosphorus retention, but studies to directly measure this relationship have not been made.

EXPERIMENTAL METHODS

Ten-day mineral balance trials were employed for directly measuring the calcium and phosphorus retention.

¹ The data presented are taken from the thesis by G. Carroll Wallis in partial fulfillment of the requirements for the degree of Ph.D., University of Minnesota, 1934. The problem was suggested by the late Dr. C. H. Eckles who acted as advisor during the first part of the work. Published with the approval of the Director as Paper 1308, Journal Series, Minnesota Agricultural Experiment Station.