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The Relative Value of Irradiated Yeast and Irradiated Ergosterol in the Production of Vitamin D Milk

Department of Agricultural Biochemistry, New Jersey Agricultural Experiment Station, New Brunswick

J. Waddell and Logan T. Wilson

Biological Laboratory, Acetol Products, Inc., New Brunswick, New Jersey
Research Laboratories, Walker-Gordon Laboratory Co., Plainsboro, New Jersey

ABSTRACT

When 60,000 units were fed per cow per day, the efficiency of irradiated ergosterol in the production of vitamin D milk is approximately the same as that of irradiated yeast. The potency of the milk was 35 to 40 units per quart. At higher levels, 180,000 units per cow per day, irradiated yeast is the more efficient product, the potency of the yeast milk being of the order of 150 to 160 rat units per quart and that of the irradiated ergosterol milk 120 to 130 units. A further increase in the daily allowance of irradiated ergosterol from 180,000 to 300,000 units caused only a slight increase in the potency of the milk.

The addition of hydroquinone increases the effectiveness of irradiated ergosterol, but to a greater extent at the lower than at the higher levels of feeding.

In the case of both products less than 2.0 per cent of the units of the antirachitic factor ingested appeared in the milk.

¹ Acetol Products Industrial Fellow. This investigation was conducted under a fellowship grant from Acetol Products, Inc., New York.