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Normal Variations in the Inorganic Phosphorus of the Blood of Dairy Cattle^*

Division of Agricultural Biochemistry and Dairy Husbandry, University of Minnesota, University Farm, St. Paul

ABSTRACT

The inorganic phosphate of the blood has been studied extensively in recent years because of its relation to various problems of nutrition, metabolism, and disease. In cattle the effect of the phosphorus level of the food on the percentage of inorganic phosphorus of the blood has already been demonstrated by us (1) (2). During the collection of these data we were impressed by the fact that unaccountable, and frequently large fluctuations may occur from day to day. This result led us to adopt the mean of the blood phosphate values obtained on three consecutive days as the probable true value. The day-to-day fluctuations, however, remained unexplained.

The physiological factors influencing the concentration of blood phosphate have not been studied extensively. Havard and Reay (3) seem to have been the only workers who have noted marked periodic fluctuations. They report that the concentration of blood phosphate is very unsteady in human blood studied at hourly intervals when the subject is not kept completely at rest.

^* Published with the approval of the Director, as Paper No. 874, Journal Series, Minnesota Agricultural Experiment Station. The data on the effects of food, water drinking, exercise, parturition and age are taken from the thesis of W. S. Cunningham, submitted in partial fulfillment for the degree of Master of Science, University of Minnesota, June, 1928.