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"Synthetic Milk" as a Basis for Research^*

Hygienic Laboratory, United States Public Health Service, Washington, D. C.

ABSTRACT

Some time ago, while attempting to formulate the chief features of the acid-base equilibria of cows' milk, my attention was called to two distressing matters of very considerable importance to milk chemistry and milk technology. In the first place I found in the enormous literature no analysis of milk sufficiently complete and at the same time sufficiently well interpreted for my purpose. One of the several deficiencies lay in the interpretation of the origins of the phosphate appearing in the ash. Without definite and unequivocal knowledge of the distribution of phosphorus between the various organic forms and the phosphate entering the buffer action of milk, there could be no assurance in the treatment of buffer indices. The second matter was the lack of adequate information upon the conduct of even simple systems in which phosphate, calcium and citrate take part simultaneously in acid-base equilibria. Without this the next important step for milk chemistry—description of the conduct of such systems in the presence of milk proteins could not even be guessed.

^* Published by permission of the Surgeon General, United States Public Health Service.